Aquaporins as targets of dietary bioactive phytocompounds

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dc.creator	Tesse, Angela
dc.creator	Grossini, Elena
dc.creator	Tamma, Grazia
dc.creator	Brenner, Catherine
dc.creator	Portincasa, Piero
dc.creator	Marinelli, Raúl A.
dc.creator	Calamita, Giuseppe
dc.date.accessioned	2021-03-01T17:57:09Z
dc.date.available	2021-03-01T17:57:09Z
dc.date.issued	2018-04-18
dc.identifier.issn	2296-889X	es
dc.identifier.uri	http://hdl.handle.net/2133/19957
dc.description	Plant-derived bioactive compounds have protective role for plants but may also modulate several physiological processes of plant consumers. In the last years, a wide spectrum of phytochemicals have been found to be beneficial to health interacting with molecular signaling pathways underlying critical functions such as cell growth and differentiation, apoptosis, autophagy, inflammation, redox balance, cell volume regulation, metabolic homeostasis, and energy balance. Hence, a large number of biologically active phytocompounds of foods have been isolated, characterized, and eventually modified representing a natural source of novel molecules to prevent, delay or cure several human diseases. Aquaporins (AQPs), a family of membrane channel proteins involved in many body functions, are emerging among the targets of bioactive phytochemicals in imparting their beneficial actions. Here, we provide a comprehensive review of this fast growing topic focusing especially on what it is known on the modulatory effects played by several edible plant and herbal compounds on AQPs, both in health and disease. Phytochemical modulation of AQP expression may provide new medical treatment options to improve the prognosis of several diseases.	es
dc.description	Para citar este articulo: Tesse A, Grossini E, Tamma G, Brenner C, Portincasa P, Marinelli RA and Calamita G (2018) Aquaporins as Targets of Dietary Bioactive Phytocompounds. Front. Mol. Biosci. 5:30. doi: 10.3389/fmolb.2018.00030
dc.format	application/pdf
dc.format.extent	1-13	es
dc.language.iso	eng	es
dc.publisher	Frontiers Media	es
dc.rights	openAccess	es
dc.rights.uri	https://creativecommons.org/licenses/by/4.0/	*
dc.subject	Aquaporin Membrane Channels	es
dc.subject	Functional Food	es
dc.subject	Nutraceutics	es
dc.subject	Epigenomics	es
dc.subject	Gastrointestinal Microbiome	es
dc.subject	Antioxidants	es
dc.subject	Anti-Inflammatory Agents	es
dc.title	Aquaporins as targets of dietary bioactive phytocompounds	es
dc.type	article
dc.type	artículo
dc.type	publishedVersion
dc.rights.holder	Universidad Nacional de Rosario	es
dc.rights.holder	Tesse, Angela	es
dc.rights.holder	Grossini, Elena	es
dc.rights.holder	Tamma, Grazia	es
dc.rights.holder	Brenner, Catherine	es
dc.rights.holder	Portincasa, Piero	es
dc.rights.holder	Marinelli, Raúl A.	es
dc.rights.holder	Calamita, Giuseppe	es
dc.relation.publisherversion	https://doi.org/10.3389/fmolb.2018.00030	es
dc.relation.publisherversion	https://www.frontiersin.org/articles/10.3389/fmolb.2018.00030/full	es
dc.rights.text	Attribution 4.0 International (CC BY 4.0)	es
dc.citation.title	Frontiers in Molecular Biosciences	es
dc.citation.volume	5	es
dc.description.fil	Fil: Tesse, Angela. Centre national de la recherche scientifique (CNRS); France.	es
dc.description.fil	Fil: Tesse, Angela. Institut National de la Santé et de la Recherche Médicale (INSERM); France.	es
dc.description.fil	Fil: Tesse, Angela. Institut du Thorax; France.	es
dc.description.fil	Fil: Tesse, Angela. Universitè de Nantes; France.	es
dc.description.fil	Fil: Grossini, Elena. University East Piedmont. Department of Translational Medicine. Laboratory of Physiology: Italy.	es
dc.description.fil	Fil: Tamma, Grazia. University of Bari “Aldo Moro”. Department of Biosciences, Biotechnologies and Biopharmaceutics; Italy.	es
dc.description.fil	Fil: Brenner, Catherine. Université Paris-Sud. LabEx LERMIT; France.	es
dc.description.fil	Fil: Brenner, Catherine. Institut National de la Santé et de la Recherche Médicale (INSERM); France.	es
dc.description.fil	Fil: Portincasa, Piero. University of Bari “Aldo Moro”. Department of Biomedical Sciences and Human Oncology, Medical School. Clinica Medica “A. Murri”; Italy.	es
dc.description.fil	Fil: Marinelli, Raúl A. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Fisiología Experimental (IFISE -CONICET); Argentina.	es
dc.description.fil	Fil: Calamita, Giuseppe. University of Bari “Aldo Moro”. Department of Biosciences, Biotechnologies and Biopharmaceutics; Italy.	es
dc.type.collection	articulo
dc.type.version	publishedVersion	es